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Increased transcription of the regulatory subunit of g-glutamylcysteine synthetase in rat lung epithelial L2 cells exposed to oxidative stress or glutathione depletion

Nevertheless, more clinical research is necessary to fully understand its impact (135)

Secondly, GA reverses TGT-induced lipid metabolism disorders, particularly restoring phosphatidylcholine (PC) and phosphatidylethanolamine (PE) metabolism, thereby maintaining hepatocyte membrane integrity and stabilizing related signal transduction functions, which aligns with the lipid remodeling phenomenon observed in TGT-induced liver injury (Shi et al., 2021

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These approaches work well when speed matters and when there is defined endpoint for treatment